null
SMILES: CC(C)COC(=O)C(=O)N[C@@H](C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1Cl
InChI Key: InChIKey=WAKDJLCHFJMMSV-YLJYHZDGSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin/Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM458399![]() (US10744104, Example 3D | US20230285340, Example 3D) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2PR8136 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM458399![]() (US10744104, Example 3D | US20230285340, Example 3D) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | US Patent | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa... | US Patent US10744104 (2020) BindingDB Entry DOI: 10.7270/Q2PG1VT4 | |||||||||||
More data for this Ligand-Target Pair |