BDBM458422 US10744104, Example 14C

SMILES: CC(C)COC(=O)C(=O)NN(C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F

InChI Key: InChIKey=OMXLJDOJWRKQPM-LJQANCHMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 458422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM458422 (US10744104, Example 14C) Show SMILES CC(C)COC(=O)C(=O)NN(C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C22H24ClFN2O6/c1-13(2)12-32-22(31)20(28)25-26(11-19(27)21(29)30)10-14-3-5-15(6-4-14)17-9-16(23)7-8-18(17)24/h3-9,13,19,27H,10-12H2,1-2H3,(H,25,28)(H,29,30)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Biopharma R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10744104 (2020)
					More data for this Ligand-Target Pair