BDBM458969 US10759794, Example 54

SMILES: CC(C)c1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)C1CCCC1

InChI Key: InChIKey=BYQKMDCONFCFPX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 458969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM458969 (US10759794, Example 54) Show SMILES CC(C)c1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C27H34N4O/c1-20(2)21-10-12-22(13-11-21)26-24(31-14-6-5-9-25(31)28-26)19-29-15-17-30(18-16-29)27(32)23-7-3-4-8-23/h5-6,9-14,20,23H,3-4,7-8,15-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020)
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM458969 (US10759794, Example 54) Show SMILES CC(C)c1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C27H34N4O/c1-20(2)21-10-12-22(13-11-21)26-24(31-14-6-5-9-25(31)28-26)19-29-15-17-30(18-16-29)27(32)23-7-3-4-8-23/h5-6,9-14,20,23H,3-4,7-8,15-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020)
					More data for this Ligand-Target Pair
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM458969 (US10759794, Example 54) Show SMILES CC(C)c1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C27H34N4O/c1-20(2)21-10-12-22(13-11-21)26-24(31-14-6-5-9-25(31)28-26)19-29-15-17-30(18-16-29)27(32)23-7-3-4-8-23/h5-6,9-14,20,23H,3-4,7-8,15-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	479	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020)
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM458969 (US10759794, Example 54) Show SMILES CC(C)c1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C27H34N4O/c1-20(2)21-10-12-22(13-11-21)26-24(31-14-6-5-9-25(31)28-26)19-29-15-17-30(18-16-29)27(32)23-7-3-4-8-23/h5-6,9-14,20,23H,3-4,7-8,15-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020)
					More data for this Ligand-Target Pair