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SMILES: COc1ccc(Cl)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=VWMGZPLBFOYJKS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM459008 (US10759794, Example 43) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H23Cl2N5O2/c1-34-22-10-9-19(27)24(29-22)25(33)31-14-12-30(13-15-31)16-20-23(17-5-7-18(26)8-6-17)28-21-4-2-3-11-32(20)21/h2-11H,12-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020)
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM459008 (US10759794, Example 43) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H23Cl2N5O2/c1-34-22-10-9-19(27)24(29-22)25(33)31-14-12-30(13-15-31)16-20-23(17-5-7-18(26)8-6-17)28-21-4-2-3-11-32(20)21/h2-11H,12-16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020)
					More data for this Ligand-Target Pair