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SMILES: COc1ccc(C)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(cc2)C#N)CC1

InChI Key: InChIKey=XLCSMRVTVQNPBL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM459033 (US10759794, Example 71) Show SMILES COc1ccc(C)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(cc2)C#N)CC1 Show InChI InChI=1S/C27H26N6O2/c1-19-6-11-24(35-2)30-25(19)27(34)32-15-13-31(14-16-32)18-22-26(21-9-7-20(17-28)8-10-21)29-23-5-3-4-12-33(22)23/h3-12H,13-16,18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM459033 (US10759794, Example 71) Show SMILES COc1ccc(C)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(cc2)C#N)CC1 Show InChI InChI=1S/C27H26N6O2/c1-19-6-11-24(35-2)30-25(19)27(34)32-15-13-31(14-16-32)18-22-26(21-9-7-20(17-28)8-10-21)29-23-5-3-4-12-33(22)23/h3-12H,13-16,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair