null

SMILES: C[C@H](O)C(=O)N1CC[C@@H](Nc2ncc(Cl)c(n2)-c2cc(F)c3ncn(c3c2)C(C)(C)C)[C@H](O)C1

InChI Key: InChIKey=QSWXQGNVXUPASL-BJOOFOGMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM462203 (US10766884, Example F21) Show SMILES C[C@H](O)C(=O)N1CC[C@@H](Nc2ncc(Cl)c(n2)-c2cc(F)c3ncn(c3c2)C(C)(C)C)[C@H](O)C1 |r| Show InChI InChI=1S/C23H28ClFN6O3/c1-12(32)21(34)30-6-5-16(18(33)10-30)28-22-26-9-14(24)19(29-22)13-7-15(25)20-17(8-13)31(11-27-20)23(2,3)4/h7-9,11-12,16,18,32-33H,5-6,10H2,1-4H3,(H,26,28,29)/t12-,16+,18+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...				US Patent US10766884 (2020)
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Homo sapiens (Human))	BDBM462203 (US10766884, Example F21) Show SMILES C[C@H](O)C(=O)N1CC[C@@H](Nc2ncc(Cl)c(n2)-c2cc(F)c3ncn(c3c2)C(C)(C)C)[C@H](O)C1 |r| Show InChI InChI=1S/C23H28ClFN6O3/c1-12(32)21(34)30-6-5-16(18(33)10-30)28-22-26-9-14(24)19(29-22)13-7-15(25)20-17(8-13)31(11-27-20)23(2,3)4/h7-9,11-12,16,18,32-33H,5-6,10H2,1-4H3,(H,26,28,29)/t12-,16+,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description CDK6/Cyclin D3: The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small mo...				US Patent US10766884 (2020)
					More data for this Ligand-Target Pair