BDBM46232 3-(methylsulfamoyl)-N-thiochroman-4-yl-benzamide::MLS-0412052.0001::N-(3,4-dihydro-2H-1-benzothiopyran-4-yl)-3-(methylsulfamoyl)benzamide::N-(3,4-dihydro-2H-thiochromen-4-yl)-3-(methylsulfamoyl)benzamide::cid_17407315

SMILES: CNS(=O)(=O)c1cccc(c1)C(=O)NC1CCSc2ccccc12

InChI Key: InChIKey=YMJQAWBOQYYFSB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 46232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46232 (3-(methylsulfamoyl)-N-thiochroman-4-yl-benzamide |...) Show SMILES CNS(=O)(=O)c1cccc(c1)C(=O)NC1CCSc2ccccc12 Show InChI InChI=1S/C17H18N2O3S2/c1-18-24(21,22)13-6-4-5-12(11-13)17(20)19-15-9-10-23-16-8-3-2-7-14(15)16/h2-8,11,15,18H,9-10H2,1H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46232 (3-(methylsulfamoyl)-N-thiochroman-4-yl-benzamide |...) Show SMILES CNS(=O)(=O)c1cccc(c1)C(=O)NC1CCSc2ccccc12 Show InChI InChI=1S/C17H18N2O3S2/c1-18-24(21,22)13-6-4-5-12(11-13)17(20)19-15-9-10-23-16-8-3-2-7-14(15)16/h2-8,11,15,18H,9-10H2,1H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21N7ZJW
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM46232 (3-(methylsulfamoyl)-N-thiochroman-4-yl-benzamide |...) Show SMILES CNS(=O)(=O)c1cccc(c1)C(=O)NC1CCSc2ccccc12 Show InChI InChI=1S/C17H18N2O3S2/c1-18-24(21,22)13-6-4-5-12(11-13)17(20)19-15-9-10-23-16-8-3-2-7-14(15)16/h2-8,11,15,18H,9-10H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28K77H7
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM46232 (3-(methylsulfamoyl)-N-thiochroman-4-yl-benzamide |...) Show SMILES CNS(=O)(=O)c1cccc(c1)C(=O)NC1CCSc2ccccc12 Show InChI InChI=1S/C17H18N2O3S2/c1-18-24(21,22)13-6-4-5-12(11-13)17(20)19-15-9-10-23-16-8-3-2-7-14(15)16/h2-8,11,15,18H,9-10H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DB807Z
					More data for this Ligand-Target Pair