BDBM46254 MLS-0412124.0001::[1-(2-phenoxyethyl)-3-indolyl]-(1-piperidinyl)methanethione::[1-(2-phenoxyethyl)indol-3-yl]-piperidin-1-yl-methanethione::[1-(2-phenoxyethyl)indol-3-yl]-piperidin-1-ylmethanethione::[1-(2-phenoxyethyl)indol-3-yl]-piperidino-methanethione::cid_44182135

SMILES: S=C(N1CCCCC1)c1cn(CCOc2ccccc2)c2ccccc12

InChI Key: InChIKey=PVTWNSAJELJREA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 46254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46254 (MLS-0412124.0001 | [1-(2-phenoxyethyl)-3-indolyl]-...) Show SMILES S=C(N1CCCCC1)c1cn(CCOc2ccccc2)c2ccccc12 Show InChI InChI=1S/C22H24N2OS/c26-22(23-13-7-2-8-14-23)20-17-24(21-12-6-5-11-19(20)21)15-16-25-18-9-3-1-4-10-18/h1,3-6,9-12,17H,2,7-8,13-16H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46254 (MLS-0412124.0001 | [1-(2-phenoxyethyl)-3-indolyl]-...) Show SMILES S=C(N1CCCCC1)c1cn(CCOc2ccccc2)c2ccccc12 Show InChI InChI=1S/C22H24N2OS/c26-22(23-13-7-2-8-14-23)20-17-24(21-12-6-5-11-19(20)21)15-16-25-18-9-3-1-4-10-18/h1,3-6,9-12,17H,2,7-8,13-16H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21N7ZJW
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM46254 (MLS-0412124.0001 | [1-(2-phenoxyethyl)-3-indolyl]-...) Show SMILES S=C(N1CCCCC1)c1cn(CCOc2ccccc2)c2ccccc12 Show InChI InChI=1S/C22H24N2OS/c26-22(23-13-7-2-8-14-23)20-17-24(21-12-6-5-11-19(20)21)15-16-25-18-9-3-1-4-10-18/h1,3-6,9-12,17H,2,7-8,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28K77H7
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM46254 (MLS-0412124.0001 | [1-(2-phenoxyethyl)-3-indolyl]-...) Show SMILES S=C(N1CCCCC1)c1cn(CCOc2ccccc2)c2ccccc12 Show InChI InChI=1S/C22H24N2OS/c26-22(23-13-7-2-8-14-23)20-17-24(21-12-6-5-11-19(20)21)15-16-25-18-9-3-1-4-10-18/h1,3-6,9-12,17H,2,7-8,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DB807Z
					More data for this Ligand-Target Pair