null
SMILES: NS(=O)(=O)OC[C@H]1C[C@H](C[C@@H]1O)Nc1ncncc1C(=O)c1cc(CC2=CCCCC2)cs1
InChI Key: InChIKey=PKTZIYNAAIIHCH-LMMKCTJWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SUMO-activating enzyme subunit 1 (Homo sapiens (Human)) | BDBM462813 (US10780090, Compound I-140 | {(1R,2S,4R)-4-[(5-{[4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. US Patent | Assay Description The SAE enzymatic reaction totals 50 μl and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 5 mM MgCl2, 0.5 μM ATP, 250 μM GSH, 0... | US Patent US10780090 (2020) BindingDB Entry DOI: 10.7270/Q29Z980S | |||||||||||
More data for this Ligand-Target Pair |