null

SMILES: OC(=O)COC[C@H]1CC[C@@H](Cn2nc(-c3ccccc3)c(cc2=O)-c2cccc(Cl)c2F)CC1

InChI Key: InChIKey=BQKNOFQKLSGVPD-HDICACEKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostacyclin receptor (Homo sapiens (Human))	BDBM464510 (2-(((1s,4s,)-4-((4-(3-chloro- 2-fluorophenyl)-6-ox...) Show SMILES OC(=O)COC[C@H]1CC[C@@H](Cn2nc(-c3ccccc3)c(cc2=O)-c2cccc(Cl)c2F)CC1 |r,wU:9.9,6.5,(9.34,-.77,;8,,;8,1.54,;6.67,-.77,;5.33,,;4,-.77,;2.67,,;1.33,-.77,;;,1.54,;-1.33,2.31,;-2.67,1.54,;-4,2.31,;-5.33,1.54,;-6.67,2.31,;-6.67,3.85,;-8,4.62,;-9.34,3.85,;-9.34,2.31,;-8,1.54,;-5.33,,;-4,-.77,;-2.67,,;-1.33,-.77,;-6.67,-.77,;-8,,;-9.34,-.77,;-9.34,-2.31,;-8,-3.08,;-8,-4.62,;-6.67,-2.31,;-5.33,-3.08,;1.33,2.31,;2.67,1.54,)| Show InChI InChI=1S/C26H26ClFN2O4/c27-22-8-4-7-20(25(22)28)21-13-23(31)30(29-26(21)19-5-2-1-3-6-19)14-17-9-11-18(12-10-17)15-34-16-24(32)33/h1-8,13,17-18H,9-12,14-16H2,(H,32,33)/t17-,18+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
ARENA PHARMACEUTICALS, INC. US Patent					Assay Description The HTRF® assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volum...				US Patent US10793529 (2020)
					More data for this Ligand-Target Pair