BDBM46726 US8906933, 3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-3-yl)-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid

SMILES: CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cccnc1

InChI Key: InChIKey=LZWHVDIVHJSYTE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 46726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
S-nitrosoglutathione reductase (GSNOR) (Homo sapiens (Human))	BDBM46726 (US8906933, 3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-...) Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cccnc1 Show InChI InChI=1S/C22H21N3O5S/c1-2-30-16-9-14(8-15(20(16)26)21(27)28)19-17(13-5-7-31-11-13)18(24-22(29)25-19)12-4-3-6-23-10-12/h3-11,17-19,26H,2H2,1H3,(H,27,28)(H2,24,25,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	22
N30 Pharmaceuticals, Inc. US Patent					Assay Description Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...				US Patent US8906933 (2014) BindingDB Entry DOI: 10.7270/Q2765D15
					More data for this Ligand-Target Pair