null

SMILES: NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1

InChI Key: InChIKey=YSJCFXZRFFIJTM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 469029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-lysine 6-oxidase (Sus scrofa)	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-A Enzyme: Promega, Cat No. V1452.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-B Enzyme: Sigma, Cat No. M7441.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Sus scrofa)	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 min at room temp on a plate shaker.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. ...				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003...				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 min at room temp on a plate shaker.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair