BDBM47039 US8906933, (R)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1H-pyrazol-4-yl)-2-oxo-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid::US8906933, (S)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1H-pyrazol-4-yl)-2-oxo-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid::US8906933, 3-ethoxy-2-hydroxy-5-(6-(1-methyl-1H-pyrazol-4-yl)-2-oxo-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid

SMILES: CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cnn(C)c1

InChI Key: InChIKey=MZVLUZLLWRFEMJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
S-nitrosoglutathione reductase (GSNOR) (Homo sapiens (Human))	BDBM47039 (US8906933, (R)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1...) Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cnn(C)c1 Show InChI InChI=1S/C21H22N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-18,26H,3H2,1-2H3,(H,27,28)(H2,23,24,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	22
N30 Pharmaceuticals, Inc. US Patent					Assay Description Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...				US Patent US8906933 (2014) BindingDB Entry DOI: 10.7270/Q2765D15
					More data for this Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR) (Homo sapiens (Human))	BDBM47039 (US8906933, (R)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1...) Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cnn(C)c1 Show InChI InChI=1S/C21H22N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-18,26H,3H2,1-2H3,(H,27,28)(H2,23,24,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	580	n/a	n/a	n/a	n/a	7.4	22
N30 Pharmaceuticals, Inc. US Patent					Assay Description Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...				US Patent US8906933 (2014) BindingDB Entry DOI: 10.7270/Q2765D15
					More data for this Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR) (Homo sapiens (Human))	BDBM47039 (US8906933, (R)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1...) Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cnn(C)c1 Show InChI InChI=1S/C21H22N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-18,26H,3H2,1-2H3,(H,27,28)(H2,23,24,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	22
N30 Pharmaceuticals, Inc. US Patent					Assay Description Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...				US Patent US8906933 (2014) BindingDB Entry DOI: 10.7270/Q2765D15
					More data for this Ligand-Target Pair