null

SMILES: CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1c(F)cccc1Cl)-n1nc([C@H](C)O)n(C)c1=O

InChI Key: InChIKey=GTQRUFUJOIEXSQ-STQMWFEESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM470473 (N-(2-chloro-6-fluorophenyl)-5-fluoro-4-{3-[(1S)-1-...) Show SMILES CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1c(F)cccc1Cl)-n1nc([C@H](C)O)n(C)c1=O |r| Show InChI InChI=1S/C23H25ClF2N4O4/c1-5-7-12(2)34-19-11-18(30-23(33)29(4)21(28-30)13(3)31)17(26)10-14(19)22(32)27-20-15(24)8-6-9-16(20)25/h6,8-13,31H,5,7H2,1-4H3,(H,27,32)/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM470473 (N-(2-chloro-6-fluorophenyl)-5-fluoro-4-{3-[(1S)-1-...) Show SMILES CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1c(F)cccc1Cl)-n1nc([C@H](C)O)n(C)c1=O |r| Show InChI InChI=1S/C23H25ClF2N4O4/c1-5-7-12(2)34-19-11-18(30-23(33)29(4)21(28-30)13(3)31)17(26)10-14(19)22(32)27-20-15(24)8-6-9-16(20)25/h6,8-13,31H,5,7H2,1-4H3,(H,27,32)/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION US Patent					Assay Description Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...				US Patent US10815215 (2020)
					More data for this Ligand-Target Pair