BDBM470479 5-fluoro-N-(2-fluoro-6-methylphenyl)-4-{3-[(1S)-1-hydroxyethyl]-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}-2-[(2S)-pentan-2-yloxy]benzamide::US10815215, Example 142

SMILES: CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1c(C)cccc1F)-n1nc([C@H](C)O)n(C)c1=O

InChI Key: InChIKey=OPBVIMWRUUSBNL-GJZGRUSLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM470479 (5-fluoro-N-(2-fluoro-6-methylphenyl)-4-{3-[(1S)-1-...) Show SMILES CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1c(C)cccc1F)-n1nc([C@H](C)O)n(C)c1=O |r| Show InChI InChI=1S/C24H28F2N4O4/c1-6-8-14(3)34-20-12-19(30-24(33)29(5)22(28-30)15(4)31)18(26)11-16(20)23(32)27-21-13(2)9-7-10-17(21)25/h7,9-12,14-15,31H,6,8H2,1-5H3,(H,27,32)/t14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM470479 (5-fluoro-N-(2-fluoro-6-methylphenyl)-4-{3-[(1S)-1-...) Show SMILES CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1c(C)cccc1F)-n1nc([C@H](C)O)n(C)c1=O |r| Show InChI InChI=1S/C24H28F2N4O4/c1-6-8-14(3)34-20-12-19(30-24(33)29(5)22(28-30)15(4)31)18(26)11-16(20)23(32)27-21-13(2)9-7-10-17(21)25/h7,9-12,14-15,31H,6,8H2,1-5H3,(H,27,32)/t14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION US Patent					Assay Description Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...				US Patent US10815215 (2020)
					More data for this Ligand-Target Pair