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SMILES: CC(C)n1cc(c(n1)C(F)(F)F)-c1cc(CN2CCN(C)C2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(F)c1

InChI Key: InChIKey=CQZFCQMZIORWIT-VWLOTQADSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473326   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473326
PNG
(US10844044, Example 216)
Show SMILES CC(C)n1cc(c(n1)C(F)(F)F)-c1cc(CN2CCN(C)C2=N)cc(c1)C(=O)N[C@@H](C1CC1)c1ccc(F)c(F)c1 |r|
Show InChI InChI=1S/C29H31F5N6O/c1-16(2)40-15-22(26(37-40)29(32,33)34)20-10-17(14-39-9-8-38(3)28(39)35)11-21(12-20)27(41)36-25(18-4-5-18)19-6-7-23(30)24(31)13-19/h6-7,10-13,15-16,18,25,35H,4-5,8-9,14H2,1-3H3,(H,36,41)/t25-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)

More data for this
Ligand-Target Pair