BindingDB logo
myBDB logout

null

SMILES: COc1cc(OC)cc(c1)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1Cl)C1CC1

InChI Key: InChIKey=FOGXPJTXBQLIJC-MHZLTWQESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473462   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473462
PNG
(US10844044, Example 249)
Show SMILES COc1cc(OC)cc(c1)[C@@H](NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1ccc(F)cc1Cl)C1CC1 |r|
Show InChI InChI=1S/C29H27ClFN3O4/c1-36-23-12-20(13-24(15-23)37-2)27(18-3-4-18)33-28(35)21-10-17(16-34-7-8-38-29(34)32)9-19(11-21)25-6-5-22(31)14-26(25)30/h5-15,18,27,32H,3-4,16H2,1-2H3,(H,33,35)/t27-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)


BindingDB Entry DOI: 10.7270/Q21R6TKB
More data for this
Ligand-Target Pair