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SMILES: Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccccc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1

InChI Key: InChIKey=QDLSYEFQYLCDRD-MHZLTWQESA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473463
PNG
(US10844044, Example 342)
Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2ccccc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r|
Show InChI InChI=1S/C30H26F4N4O/c1-18-13-21(9-10-25(18)31)27(20-7-8-20)37-29(39)23-15-19(17-38-12-3-2-6-26(38)35)14-22(16-23)24-5-4-11-36-28(24)30(32,33)34/h2-6,9-16,20,27,35H,7-8,17H2,1H3,(H,37,39)/t27-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)


BindingDB Entry DOI: 10.7270/Q21R6TKB
More data for this
Ligand-Target Pair