BDBM473478 US10844044, Example 253

SMILES: Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCOC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1

InChI Key: InChIKey=LIHADAJRNWQKGW-DEOSSOPVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM473478 (US10844044, Example 253) Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCOC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C28H26F4N4O2/c1-16-11-19(6-7-23(16)29)24(18-4-5-18)35-26(37)21-13-17(15-36-9-10-38-27(36)33)12-20(14-21)22-3-2-8-34-25(22)28(30,31)32/h2-3,6-8,11-14,18,24,33H,4-5,9-10,15H2,1H3,(H,35,37)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...				US Patent US10844044 (2020)
					More data for this Ligand-Target Pair