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SMILES: CCOc1c(cc(Cn2ccccc2=N)cc1-c1cn(C)nc1C(F)(F)F)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1

InChI Key: InChIKey=NXOBTXPUNSOYEU-MHZLTWQESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473483   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473483
PNG
(US10844044, Example 347)
Show SMILES CCOc1c(cc(Cn2ccccc2=N)cc1-c1cn(C)nc1C(F)(F)F)C(=O)N[C@@H](C1CC1)c1ccc(F)c(C)c1 |r|
Show InChI InChI=1S/C31H31F4N5O2/c1-4-42-28-22(24-17-39(3)38-29(24)31(33,34)35)14-19(16-40-12-6-5-7-26(40)36)15-23(28)30(41)37-27(20-8-9-20)21-10-11-25(32)18(2)13-21/h5-7,10-15,17,20,27,36H,4,8-9,16H2,1-3H3,(H,37,41)/t27-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)

More data for this
Ligand-Target Pair