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SMILES: Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2cccc(F)c2=N)cc(c1)-c1cn(C)nc1C(F)(F)F)C1CC1

InChI Key: InChIKey=CIKKRXNFSNBVPK-VWLOTQADSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473499   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473499
PNG
(US10844044, Example 351)
Show SMILES Cc1cc(ccc1F)[C@@H](NC(=O)c1cc(Cn2cccc(F)c2=N)cc(c1)-c1cn(C)nc1C(F)(F)F)C1CC1 |r|
Show InChI InChI=1S/C29H26F5N5O/c1-16-10-19(7-8-23(16)30)25(18-5-6-18)36-28(40)21-12-17(14-39-9-3-4-24(31)27(39)35)11-20(13-21)22-15-38(2)37-26(22)29(32,33)34/h3-4,7-13,15,18,25,35H,5-6,14H2,1-2H3,(H,36,40)/t25-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)

More data for this
Ligand-Target Pair