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SMILES: CCC(=O)CNC(=O)CC(NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ccc(F)cc1C(F)(F)F)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=JRSHGFVWYWHAEP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473532   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473532
PNG
(US10844044, Example 85)
Show SMILES CCC(=O)CNC(=O)CC(NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1ccc(F)cc1C(F)(F)F)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C32H29Cl2F4N5O3/c1-3-23(44)16-40-29(45)15-28(19-4-7-26(33)27(34)13-19)41-30(46)21-11-18(17-43-9-8-42(2)31(43)39)10-20(12-21)24-6-5-22(35)14-25(24)32(36,37)38/h4-14,28,39H,3,15-17H2,1-2H3,(H,40,45)(H,41,46)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)


BindingDB Entry DOI: 10.7270/Q21R6TKB
More data for this
Ligand-Target Pair