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SMILES: Cc1cccc(c1)S(=O)(=O)c1cc2nc([nH]c2cc1Cl)-n1cc(cn1)C(O)=O

InChI Key: InChIKey=YHIPPOAJRPXQIE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475470   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1 [181-417]


(Homo sapiens (Human))		BDBM475470
PNG
(1-[6-Chloro-5-(toluene-3-sulfonyl)-1H-benzoimidazo...)
Show SMILES Cc1cccc(c1)S(=O)(=O)c1cc2nc([nH]c2cc1Cl)-n1cc(cn1)C(O)=O
Show InChI InChI=1S/C18H13ClN4O4S/c1-10-3-2-4-12(5-10)28(26,27)16-7-15-14(6-13(16)19)21-18(22-15)23-9-11(8-20-23)17(24)25/h2-9H,1H3,(H,21,22)(H,24,25)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 39.8n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...

US Patent US10851083 (2020)

More data for this
Ligand-Target Pair