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SMILES: CCS(=O)(=O)c1cc2[nH]c(nc2cc1Cl)-n1cc(cn1)C(O)=O

InChI Key: InChIKey=JQSUSMZMRBCOON-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475484 (1-(5-Chloro-6-ethanesulfonyl-1H-benzoimidazol-2-yl...) Show SMILES CCS(=O)(=O)c1cc2[nH]c(nc2cc1Cl)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C13H11ClN4O4S/c1-2-23(21,22)11-4-10-9(3-8(11)14)16-13(17-10)18-6-7(5-15-18)12(19)20/h3-6H,2H2,1H3,(H,16,17)(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475484 (1-(5-Chloro-6-ethanesulfonyl-1H-benzoimidazol-2-yl...) Show SMILES CCS(=O)(=O)c1cc2[nH]c(nc2cc1Cl)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C13H11ClN4O4S/c1-2-23(21,22)11-4-10-9(3-8(11)14)16-13(17-10)18-6-7(5-15-18)12(19)20/h3-6H,2H2,1H3,(H,16,17)(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair