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SMILES: CS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O

InChI Key: InChIKey=ZPXPIKXZUOSBAS-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475488   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1 [181-417]


(Homo sapiens (Human))		BDBM475488
PNG
(1-(6-Methanesulfonyl-5-trifluoromethoxy-1H- | US10...)
Show SMILES CS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O
Show InChI InChI=1S/C13H9F3N4O5S/c1-26(23,24)10-3-8-7(2-9(10)25-13(14,15)16)18-12(19-8)20-5-6(4-17-20)11(21)22/h2-5H,1H3,(H,18,19)(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 31.6n/an/an/an/an/an/a


TBA

Assay Description
The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2V69PHV
More data for this
Ligand-Target Pair
Egl nine homolog 1 [181-417]


(Homo sapiens (Human))		BDBM475488
PNG
(1-(6-Methanesulfonyl-5-trifluoromethoxy-1H- | US10...)
Show SMILES CS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O
Show InChI InChI=1S/C13H9F3N4O5S/c1-26(23,24)10-3-8-7(2-9(10)25-13(14,15)16)18-12(19-8)20-5-6(4-17-20)11(21)22/h2-5H,1H3,(H,18,19)(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 31.6n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...

US Patent US10851083 (2020)


BindingDB Entry DOI: 10.7270/Q25B05K9
More data for this
Ligand-Target Pair