null
SMILES: CC(C)S(=O)(=O)c1cc2[nH]c(nc2cc1C(F)(F)F)-n1cc(cn1)C(O)=O
InChI Key: InChIKey=XXDAMRZVFAHDMA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Egl nine homolog 1 [181-417] (Homo sapiens (Human)) | BDBM475491![]() (1-[6-(Propane-2-sulfonyl)-5-trifluoromethyl-1H- | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep... | Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Egl nine homolog 1 [181-417] (Homo sapiens (Human)) | BDBM475491![]() (1-[6-(Propane-2-sulfonyl)-5-trifluoromethyl-1H- | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept... | US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9 | |||||||||||
More data for this Ligand-Target Pair |