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SMILES: OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1c(Cl)cccc1Cl

InChI Key: InChIKey=GPVMDBWYXDAPDY-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475565   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1 [181-417]


(Homo sapiens (Human))		BDBM475565
PNG
(1-[6-Chloro-5-(2,6-dichloro-phenylmethanesulfonyl)...)
Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1c(Cl)cccc1Cl
Show InChI InChI=1S/C18H11Cl3N4O4S/c19-11-2-1-3-12(20)10(11)8-30(28,29)16-5-15-14(4-13(16)21)23-18(24-15)25-7-9(6-22-25)17(26)27/h1-7H,8H2,(H,23,24)(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 31.6n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...

US Patent US10851083 (2020)

More data for this
Ligand-Target Pair