Found 4 hits for monomerid = 475994 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ubiquitin-like modifier-activating enzyme ATG7
(Homo sapiens (Human)) | BDBM475994
(US10865208, Compound I-52 | {(2R,3S,4R,5R)-5-[4-am...)Show SMILES Nc1ncnc2n(nc(SCc3ccccc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H20N6O6S2/c18-14-11-15(21-8-20-14)23(22-16(11)30-7-9-4-2-1-3-5-9)17-13(25)12(24)10(29-17)6-28-31(19,26)27/h1-5,8,10,12-13,17,24-25H,6-7H2,(H2,18,20,21)(H2,19,26,27)/t10-,12-,13-,17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
| Assay Description The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ... |
US Patent US10865208 (2020)
|
More data for this Ligand-Target Pair | |
Ubiquitin-like modifier-activating enzyme ATG7
(Homo sapiens (Human)) | BDBM475994
(US10865208, Compound I-52 | {(2R,3S,4R,5R)-5-[4-am...)Show SMILES Nc1ncnc2n(nc(SCc3ccccc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H20N6O6S2/c18-14-11-15(21-8-20-14)23(22-16(11)30-7-9-4-2-1-3-5-9)17-13(25)12(24)10(29-17)6-28-31(19,26)27/h1-5,8,10,12-13,17,24-25H,6-7H2,(H2,18,20,21)(H2,19,26,27)/t10-,12-,13-,17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 322 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Ubiquitin-like modifier-activating enzyme ATG7
(Homo sapiens (Human)) | BDBM475994
(US10865208, Compound I-52 | {(2R,3S,4R,5R)-5-[4-am...)Show SMILES Nc1ncnc2n(nc(SCc3ccccc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H20N6O6S2/c18-14-11-15(21-8-20-14)23(22-16(11)30-7-9-4-2-1-3-5-9)17-13(25)12(24)10(29-17)6-28-31(19,26)27/h1-5,8,10,12-13,17,24-25H,6-7H2,(H2,18,20,21)(H2,19,26,27)/t10-,12-,13-,17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 604 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Ubiquitin-like modifier-activating enzyme ATG7
(Homo sapiens (Human)) | BDBM475994
(US10865208, Compound I-52 | {(2R,3S,4R,5R)-5-[4-am...)Show SMILES Nc1ncnc2n(nc(SCc3ccccc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H20N6O6S2/c18-14-11-15(21-8-20-14)23(22-16(11)30-7-9-4-2-1-3-5-9)17-13(25)12(24)10(29-17)6-28-31(19,26)27/h1-5,8,10,12-13,17,24-25H,6-7H2,(H2,18,20,21)(H2,19,26,27)/t10-,12-,13-,17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |