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SMILES: COC(C)Cc1ccc(NS(=O)(=O)C2=CC3C(C=C2Br)C(C)(C)CCC3(C)C)cc1

InChI Key: InChIKey=KTKWRYFUVKVPFK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476221   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 26A1


(Homo sapiens (Human))		BDBM476221
PNG
(US10874634, Cmpd No. 04B)
Show SMILES COC(C)Cc1ccc(NS(=O)(=O)C2=CC3C(C=C2Br)C(C)(C)CCC3(C)C)cc1 |c:17,t:13|
Show InChI InChI=1S/C24H34BrNO3S/c1-16(29-6)13-17-7-9-18(10-8-17)26-30(27,28)22-15-20-19(14-21(22)25)23(2,3)11-12-24(20,4)5/h7-10,14-16,19-20,26H,11-13H2,1-6H3
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US Patent
n/an/a 8.24E+3n/an/an/an/an/an/a



Queen''s University at Kingston

US Patent


Assay Description
CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...

US Patent US10874634 (2020)

More data for this
Ligand-Target Pair