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SMILES: Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C

InChI Key: InChIKey=QWFCVDPZBKASNN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 26A1 (Homo sapiens (Human))	BDBM476228 (US10874634, Cmpd No. 10 | US11364220, Compound 10) Show SMILES Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	8.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020)
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476228 (US10874634, Cmpd No. 10 | US11364220, Compound 10) Show SMILES Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 26A1 (Homo sapiens (Human))	BDBM476228 (US10874634, Cmpd No. 10 | US11364220, Compound 10) Show SMILES Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem		n/a	n/a	8.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476228 (US10874634, Cmpd No. 10 | US11364220, Compound 10) Show SMILES Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020)
					More data for this Ligand-Target Pair