null

SMILES: C[C@H]1CN(Cc2cc(Nc3ncc(Cl)c(n3)-c3c[nH]c4cc(C)ccc34)cc(c2)C2CC2)C[C@@H](C)N1CCO

InChI Key: InChIKey=WMFRVZTYALPKJC-OYRHEFFESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM476698 (2-((2R,6S)-4-(3-((5-chloro-4-(6-methyl-1H-indole-3...) Show SMILES C[C@H]1CN(Cc2cc(Nc3ncc(Cl)c(n3)-c3c[nH]c4cc(C)ccc34)cc(c2)C2CC2)C[C@@H](C)N1CCO Show InChI InChI=1S/C31H37ClN6O/c1-19-4-7-26-27(14-33-29(26)10-19)30-28(32)15-34-31(36-30)35-25-12-22(11-24(13-25)23-5-6-23)18-37-16-20(2)38(8-9-39)21(3)17-37/h4,7,10-15,20-21,23,33,39H,5-6,8-9,16-18H2,1-3H3,(H,34,35,36)/t20-,21+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM476698 (2-((2R,6S)-4-(3-((5-chloro-4-(6-methyl-1H-indole-3...) Show SMILES C[C@H]1CN(Cc2cc(Nc3ncc(Cl)c(n3)-c3c[nH]c4cc(C)ccc34)cc(c2)C2CC2)C[C@@H](C)N1CCO Show InChI InChI=1S/C31H37ClN6O/c1-19-4-7-26-27(14-33-29(26)10-19)30-28(32)15-34-31(36-30)35-25-12-22(11-24(13-25)23-5-6-23)18-37-16-20(2)38(8-9-39)21(3)17-37/h4,7,10-15,20-21,23,33,39H,5-6,8-9,16-18H2,1-3H3,(H,34,35,36)/t20-,21+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
HANMI PHARM. CO.. LTD. US Patent					Assay Description The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...				US Patent US10870639 (2020)
					More data for this Ligand-Target Pair