Found 4 hits for monomerid = 476816 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM476816
(US10870660, Compound III-280 | US11345716, Compoun...)Show SMILES FC(F)COc1nc2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccc4CC(=O)Nc34)CCc2s1 |r,wU:13.12,wD:16.19,(-11.13,-5.29,;-11.13,-3.75,;-12.47,-2.98,;-9.8,-2.98,;-8.47,-3.75,;-7.13,-2.98,;-6.97,-1.44,;-5.46,-1.12,;-4.9,.31,;-3.43,.76,;-2.16,-.1,;-.82,.67,;.51,-.1,;1.84,.67,;1.84,2.21,;3.18,2.98,;4.51,2.21,;4.51,.67,;3.18,-.1,;5.84,2.98,;7.18,2.21,;7.18,.67,;8.51,2.98,;8.51,4.52,;9.84,5.29,;11.18,4.52,;11.18,2.98,;12.32,1.95,;11.7,.54,;12.47,-.8,;10.17,.7,;9.84,2.21,;-2.04,-1.64,;-3.17,-2.69,;-4.69,-2.46,;-5.73,-3.6,)| Show InChI InChI=1S/C26H32F2N4O3S/c27-22(28)15-35-26-30-20-9-12-32(13-10-21(20)36-26)11-8-16-4-6-18(7-5-16)29-25(34)19-3-1-2-17-14-23(33)31-24(17)19/h1-3,16,18,22H,4-15H2,(H,29,34)(H,31,33)/t16-,18- | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SHIONOGI & CO., LTD.
US Patent
| Assay Description
225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent... |
US Patent US10870660 (2020)
|
More data for this
Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM476816
(US10870660, Compound III-280 | US11345716, Compoun...)Show SMILES FC(F)COc1nc2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccc4CC(=O)Nc34)CCc2s1 |r,wU:13.12,wD:16.19,(-11.13,-5.29,;-11.13,-3.75,;-12.47,-2.98,;-9.8,-2.98,;-8.47,-3.75,;-7.13,-2.98,;-6.97,-1.44,;-5.46,-1.12,;-4.9,.31,;-3.43,.76,;-2.16,-.1,;-.82,.67,;.51,-.1,;1.84,.67,;1.84,2.21,;3.18,2.98,;4.51,2.21,;4.51,.67,;3.18,-.1,;5.84,2.98,;7.18,2.21,;7.18,.67,;8.51,2.98,;8.51,4.52,;9.84,5.29,;11.18,4.52,;11.18,2.98,;12.32,1.95,;11.7,.54,;12.47,-.8,;10.17,.7,;9.84,2.21,;-2.04,-1.64,;-3.17,-2.69,;-4.69,-2.46,;-5.73,-3.6,)| Show InChI InChI=1S/C26H32F2N4O3S/c27-22(28)15-35-26-30-20-9-12-32(13-10-21(20)36-26)11-8-16-4-6-18(7-5-16)29-25(34)19-3-1-2-17-14-23(33)31-24(17)19/h1-3,16,18,22H,4-15H2,(H,29,34)(H,31,33)/t16-,18- | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM476816
(US10870660, Compound III-280 | US11345716, Compoun...)Show SMILES FC(F)COc1nc2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccc4CC(=O)Nc34)CCc2s1 |r,wU:13.12,wD:16.19,(-11.13,-5.29,;-11.13,-3.75,;-12.47,-2.98,;-9.8,-2.98,;-8.47,-3.75,;-7.13,-2.98,;-6.97,-1.44,;-5.46,-1.12,;-4.9,.31,;-3.43,.76,;-2.16,-.1,;-.82,.67,;.51,-.1,;1.84,.67,;1.84,2.21,;3.18,2.98,;4.51,2.21,;4.51,.67,;3.18,-.1,;5.84,2.98,;7.18,2.21,;7.18,.67,;8.51,2.98,;8.51,4.52,;9.84,5.29,;11.18,4.52,;11.18,2.98,;12.32,1.95,;11.7,.54,;12.47,-.8,;10.17,.7,;9.84,2.21,;-2.04,-1.64,;-3.17,-2.69,;-4.69,-2.46,;-5.73,-3.6,)| Show InChI InChI=1S/C26H32F2N4O3S/c27-22(28)15-35-26-30-20-9-12-32(13-10-21(20)36-26)11-8-16-4-6-18(7-5-16)29-25(34)19-3-1-2-17-14-23(33)31-24(17)19/h1-3,16,18,22H,4-15H2,(H,29,34)(H,31,33)/t16-,18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM476816
(US10870660, Compound III-280 | US11345716, Compoun...)Show SMILES FC(F)COc1nc2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccc4CC(=O)Nc34)CCc2s1 |r,wU:13.12,wD:16.19,(-11.13,-5.29,;-11.13,-3.75,;-12.47,-2.98,;-9.8,-2.98,;-8.47,-3.75,;-7.13,-2.98,;-6.97,-1.44,;-5.46,-1.12,;-4.9,.31,;-3.43,.76,;-2.16,-.1,;-.82,.67,;.51,-.1,;1.84,.67,;1.84,2.21,;3.18,2.98,;4.51,2.21,;4.51,.67,;3.18,-.1,;5.84,2.98,;7.18,2.21,;7.18,.67,;8.51,2.98,;8.51,4.52,;9.84,5.29,;11.18,4.52,;11.18,2.98,;12.32,1.95,;11.7,.54,;12.47,-.8,;10.17,.7,;9.84,2.21,;-2.04,-1.64,;-3.17,-2.69,;-4.69,-2.46,;-5.73,-3.6,)| Show InChI InChI=1S/C26H32F2N4O3S/c27-22(28)15-35-26-30-20-9-12-32(13-10-21(20)36-26)11-8-16-4-6-18(7-5-16)29-25(34)19-3-1-2-17-14-23(33)31-24(17)19/h1-3,16,18,22H,4-15H2,(H,29,34)(H,31,33)/t16-,18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SHIONOGI & CO., LTD.
US Patent
| Assay Description
225 nL of the solutions of the non-specific ligand or the compounds of the present invention at each concentration (in case of vehicle, final concent... |
US Patent US10870660 (2020)
|
More data for this
Ligand-Target Pair | |
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