BDBM47721 MLS000523066::N-[2-[6-[4-(2,5-dimethylphenyl)piperazin-1-yl]carbonyl-3-oxidanylidene-4H-quinoxalin-2-yl]phenyl]ethanamide::N-[2-[6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-3-keto-4H-quinoxalin-2-yl]phenyl]acetamide::N-[2-[6-[4-(2,5-dimethylphenyl)piperazine-1-carbonyl]-3-oxo-4H-quinoxalin-2-yl]phenyl]acetamide::N-[2-[6-[[4-(2,5-dimethylphenyl)-1-piperazinyl]-oxomethyl]-3-oxo-4H-quinoxalin-2-yl]phenyl]acetamide::SMR000128332::cid_9551426

SMILES: CC(=O)Nc1ccccc1-c1nc2ccc(cc2[nH]c1=O)C(=O)N1CCN(CC1)c1cc(C)ccc1C

InChI Key: InChIKey=DDYFSFPWRLZAMB-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RGS7 (Homo sapiens (Human))	BDBM47721 (MLS000523066 | N-[2-[6-[4-(2,5-dimethylphenyl)pipe...) Show SMILES CC(=O)Nc1ccccc1-c1nc2ccc(cc2[nH]c1=O)C(=O)N1CCN(CC1)c1cc(C)ccc1C Show InChI InChI=1S/C29H29N5O3/c1-18-8-9-19(2)26(16-18)33-12-14-34(15-13-33)29(37)21-10-11-24-25(17-21)32-28(36)27(31-24)22-6-4-5-7-23(22)30-20(3)35/h4-11,16-17H,12-15H2,1-3H3,(H,30,35)(H,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM47721 (MLS000523066 | N-[2-[6-[4-(2,5-dimethylphenyl)pipe...) Show SMILES CC(=O)Nc1ccccc1-c1nc2ccc(cc2[nH]c1=O)C(=O)N1CCN(CC1)c1cc(C)ccc1C Show InChI InChI=1S/C29H29N5O3/c1-18-8-9-19(2)26(16-18)33-12-14-34(15-13-33)29(37)21-10-11-24-25(17-21)32-28(36)27(31-24)22-6-4-5-7-23(22)30-20(3)35/h4-11,16-17H,12-15H2,1-3H3,(H,30,35)(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47721 (MLS000523066 | N-[2-[6-[4-(2,5-dimethylphenyl)pipe...) Show SMILES CC(=O)Nc1ccccc1-c1nc2ccc(cc2[nH]c1=O)C(=O)N1CCN(CC1)c1cc(C)ccc1C Show InChI InChI=1S/C29H29N5O3/c1-18-8-9-19(2)26(16-18)33-12-14-34(15-13-33)29(37)21-10-11-24-25(17-21)32-28(36)27(31-24)22-6-4-5-7-23(22)30-20(3)35/h4-11,16-17H,12-15H2,1-3H3,(H,30,35)(H,32,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47721 (MLS000523066 | N-[2-[6-[4-(2,5-dimethylphenyl)pipe...) Show SMILES CC(=O)Nc1ccccc1-c1nc2ccc(cc2[nH]c1=O)C(=O)N1CCN(CC1)c1cc(C)ccc1C Show InChI InChI=1S/C29H29N5O3/c1-18-8-9-19(2)26(16-18)33-12-14-34(15-13-33)29(37)21-10-11-24-25(17-21)32-28(36)27(31-24)22-6-4-5-7-23(22)30-20(3)35/h4-11,16-17H,12-15H2,1-3H3,(H,30,35)(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47721 (MLS000523066 | N-[2-[6-[4-(2,5-dimethylphenyl)pipe...) Show SMILES CC(=O)Nc1ccccc1-c1nc2ccc(cc2[nH]c1=O)C(=O)N1CCN(CC1)c1cc(C)ccc1C Show InChI InChI=1S/C29H29N5O3/c1-18-8-9-19(2)26(16-18)33-12-14-34(15-13-33)29(37)21-10-11-24-25(17-21)32-28(36)27(31-24)22-6-4-5-7-23(22)30-20(3)35/h4-11,16-17H,12-15H2,1-3H3,(H,30,35)(H,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair