BDBM477473 N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(5-oxo-4,5-::US10889555, Example 243A
SMILES: C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2[C@@H](O)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human)) | BDBM477473![]() (N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ... | US Patent US10889555 (2021) | |||||||||||
More data for this Ligand-Target Pair |