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SMILES: COc1nc(N[C@@H]2CCN(C2)C(=O)c2ccc3N(CCCc3c2)C(=O)C=C)ncc1Cl

InChI Key: InChIKey=UUHGVRCHSWHDGO-MRXNPFEDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 12 (Homo sapiens)	BDBM478963 ((R)-1-(6-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...) Show SMILES COc1nc(N[C@@H]2CCN(C2)C(=O)c2ccc3N(CCCc3c2)C(=O)C=C)ncc1Cl |r| Show InChI InChI=1S/C22H24ClN5O3/c1-3-19(29)28-9-4-5-14-11-15(6-7-18(14)28)21(30)27-10-8-16(13-27)25-22-24-12-17(23)20(26-22)31-2/h3,6-7,11-12,16H,1,4-5,8-10,13H2,2H3,(H,24,25,26)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
KINNATE BIOPHARMA INC. US Patent					Assay Description For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...				US Patent US10894788 (2021)
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 12 (Homo sapiens)	BDBM478963 ((R)-1-(6-(3-((5-chloro-4- methoxypyrimidin-2- yl)a...) Show SMILES COc1nc(N[C@@H]2CCN(C2)C(=O)c2ccc3N(CCCc3c2)C(=O)C=C)ncc1Cl |r| Show InChI InChI=1S/C22H24ClN5O3/c1-3-19(29)28-9-4-5-14-11-15(6-7-18(14)28)21(30)27-10-8-16(13-27)25-22-24-12-17(23)20(26-22)31-2/h3,6-7,11-12,16H,1,4-5,8-10,13H2,2H3,(H,24,25,26)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
KINNATE BIOPHARMA INC. US Patent					Assay Description For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...				US Patent US10894788 (2021)
					More data for this Ligand-Target Pair