null

SMILES: C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@H](C[C@H]5COc34)OC(N)=O)nc2CO)[C@@H]1N

InChI Key: InChIKey=GPMCVSXTDRZSLO-VCAMNPENSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 479333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM479333 ((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@H](C[C@H]5COc34)OC(N)=O)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C25H33N7O5S/c1-14-21(26)25(13-36-14)3-6-31(7-4-25)22-17(11-33)30-19(9-29-22)38-18-2-5-28-23-20(18)35-12-15-8-16(10-32(15)23)37-24(27)34/h2,5,9,14-16,21,33H,3-4,6-8,10-13,26H2,1H3,(H2,27,34)/t14-,15-,16-,21+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Nikang Therapeutics, Inc. US Patent					Assay Description SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...				US Patent US10894797 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM479333 ((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@H](C[C@H]5COc34)OC(N)=O)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C25H33N7O5S/c1-14-21(26)25(13-36-14)3-6-31(7-4-25)22-17(11-33)30-19(9-29-22)38-18-2-5-28-23-20(18)35-12-15-8-16(10-32(15)23)37-24(27)34/h2,5,9,14-16,21,33H,3-4,6-8,10-13,26H2,1H3,(H2,27,34)/t14-,15-,16-,21+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
SH2B adapter protein 2 (Human)	BDBM479333 ((6aS,8S)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@H](C[C@H]5COc34)OC(N)=O)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C25H33N7O5S/c1-14-21(26)25(13-36-14)3-6-31(7-4-25)22-17(11-33)30-19(9-29-22)38-18-2-5-28-23-20(18)35-12-15-8-16(10-32(15)23)37-24(27)34/h2,5,9,14-16,21,33H,3-4,6-8,10-13,26H2,1H3,(H2,27,34)/t14-,15-,16-,21+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair