null
SMILES: COc1ccc(CNc2c3CNCCc3nc3ccc(Br)cc23)cc1Cl
InChI Key: InChIKey=XNXGPHBXUMZYND-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM480489 (US10899756, Compound F) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) | |||||||||||
More data for this Ligand-Target Pair |