null

SMILES: CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(c(cc12)C(F)F)-n1cnc(C)c1

InChI Key: InChIKey=BVNSMRUDPSJEIU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM480527 (3-cyclopropyl-1-(3-(difluoromethyl)-2-(4-methyl-1H...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(c(cc12)C(F)F)-n1cnc(C)c1 Show InChI InChI=1S/C25H24F2N6O/c1-13-10-32(12-28-13)24-18(22(26)27)9-17-16(5-4-6-19(17)29-24)21-20-11-31(3)25(34)14(2)33(20)23(30-21)15-7-8-15/h4-6,9-10,12,14-15,22H,7-8,11H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480527 (3-cyclopropyl-1-(3-(difluoromethyl)-2-(4-methyl-1H...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(c(cc12)C(F)F)-n1cnc(C)c1 Show InChI InChI=1S/C25H24F2N6O/c1-13-10-32(12-28-13)24-18(22(26)27)9-17-16(5-4-6-19(17)29-24)21-20-11-31(3)25(34)14(2)33(20)23(30-21)15-7-8-15/h4-6,9-10,12,14-15,22H,7-8,11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair