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SMILES: C[C@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F

InChI Key: InChIKey=QCVBUWRWHOLCOJ-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480542   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM480542 (US10899769, Example 26a) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F |r| Show InChI InChI=1S/C27H27F3N6O2/c1-15-26(37)34(2)14-22-24(33-25(36(15)22)16-7-9-38-10-8-16)18-5-4-6-21-19(18)11-20(27(28,29)30)23(32-21)17-12-31-35(3)13-17/h4-6,11-13,15-16H,7-10,14H2,1-3H3/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021)
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480542 (US10899769, Example 26a) Show SMILES C[C@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F |r| Show InChI InChI=1S/C27H27F3N6O2/c1-15-26(37)34(2)14-22-24(33-25(36(15)22)16-7-9-38-10-8-16)18-5-4-6-21-19(18)11-20(27(28,29)30)23(32-21)17-12-31-35(3)13-17/h4-6,11-13,15-16H,7-10,14H2,1-3H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021)
					More data for this Ligand-Target Pair