null

SMILES: CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cn(C)cn1

InChI Key: InChIKey=BKOMFGNROQEUHF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM480594 (3-cyclopropyl-5,7- dimethyl-1-(3-(1-methyl- 1H-imi...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cn(C)cn1 Show InChI InChI=1S/C24H24N6O/c1-14-24(31)29(3)12-21-22(27-23(30(14)21)15-7-8-15)17-6-4-5-16-9-19(25-10-18(16)17)20-11-28(2)13-26-20/h4-6,9-11,13-15H,7-8,12H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480594 (3-cyclopropyl-5,7- dimethyl-1-(3-(1-methyl- 1H-imi...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cn(C)cn1 Show InChI InChI=1S/C24H24N6O/c1-14-24(31)29(3)12-21-22(27-23(30(14)21)15-7-8-15)17-6-4-5-16-9-19(25-10-18(16)17)20-11-28(2)13-26-20/h4-6,9-11,13-15H,7-8,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair