null
SMILES: CC1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1ccn(C)n1
InChI Key: InChIKey=FQVGCUZGXCCGOC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human)) | BDBM480603![]() (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in... | US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CREB-binding protein [1081-1197] (Homo sapiens (Human)) | BDBM480603![]() (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 232 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in... | US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human)) | BDBM480603![]() (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in... | US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CREB-binding protein [1081-1197] (Homo sapiens (Human)) | BDBM480603![]() (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in... | US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ | |||||||||||
More data for this Ligand-Target Pair |