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SMILES: C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N

InChI Key: InChIKey=OTLUGLDCVHKZEE-MRXNPFEDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein [1081-1197] (Homo sapiens (Human))	BDBM480636 (US10899769, Example 8b) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N |r| Show InChI InChI=1S/C27H27N7O2/c1-16-27(35)32(2)15-23-25(31-26(34(16)23)17-7-9-36-10-8-17)20-5-4-6-22-21(20)11-18(12-28)24(30-22)19-13-29-33(3)14-19/h4-6,11,13-14,16-17H,7-10,15H2,1-3H3/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480636 (US10899769, Example 8b) Show SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N |r| Show InChI InChI=1S/C27H27N7O2/c1-16-27(35)32(2)15-23-25(31-26(34(16)23)17-7-9-36-10-8-17)20-5-4-6-22-21(20)11-18(12-28)24(30-22)19-13-29-33(3)14-19/h4-6,11,13-14,16-17H,7-10,15H2,1-3H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair