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SMILES: Cn1cc(-c2cccc(NS(=O)(=O)c3cc(F)c(Br)cc3F)c2F)c2c(N)ncnc12

InChI Key: InChIKey=FOQSCFGLUDRRJN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482201   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Eukaryotic translation initiation factor 2-alpha kinase 3


(Homo sapiens (Human))		BDBM482201
PNG
(N-[3-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Show SMILES Cn1cc(-c2cccc(NS(=O)(=O)c3cc(F)c(Br)cc3F)c2F)c2c(N)ncnc12
Show InChI InChI=1S/C19H13BrF3N5O2S/c1-28-7-10(16-18(24)25-8-26-19(16)28)9-3-2-4-14(17(9)23)27-31(29,30)15-6-12(21)11(20)5-13(15)22/h2-8,27H,1H3,(H2,24,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<16n/an/an/an/an/an/a



Nerviano Medical Sciences S.R.L.

US Patent


Assay Description
Compounds were 3-fold serially diluted in order to obtain from 3.333 to 0.000169 microM final concentration, then incubated for 60 minutes at room te...

US Patent US10918642 (2021)

More data for this
Ligand-Target Pair