null

SMILES: Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2C(CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl

InChI Key: InChIKey=LUUVVFYWJPDWBI-VLUDLIOXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482304 (US10919852, Compound TABLE 1.3 | US11708326, Compo...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2C(CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r| Show InChI InChI=1S/C46H51ClN4O5/c1-30-36(7-5-12-43(30)54-20-6-17-51-18-15-35(52)16-19-51)37-8-4-9-39-38(37)13-14-44(39)56-46-25-45(55-29-33-22-31(26-48)21-32(23-33)27-49)34(24-40(46)47)28-50-41-10-2-3-11-42(41)53/h4-5,7-9,12,21-25,35,41-42,44,50,52-53H,2-3,6,10-11,13-20,28-29H2,1H3/t41-,42+,44?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482304 (US10919852, Compound TABLE 1.3 | US11708326, Compo...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2C(CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r| Show InChI InChI=1S/C46H51ClN4O5/c1-30-36(7-5-12-43(30)54-20-6-17-51-18-15-35(52)16-19-51)37-8-4-9-39-38(37)13-14-44(39)56-46-25-45(55-29-33-22-31(26-48)21-32(23-33)27-49)34(24-40(46)47)28-50-41-10-2-3-11-42(41)53/h4-5,7-9,12,21-25,35,41-42,44,50,52-53H,2-3,6,10-11,13-20,28-29H2,1H3/t41-,42+,44?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair