BDBM482309 US10919852, Compound TABLE 1.8

SMILES: CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)c(Cl)cc1CN[C@@H]([C@@H](C)O)C(O)=O

InChI Key: InChIKey=SSBHVSUUYKUGJK-LKECHTOISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482309 (US10919852, Compound TABLE 1.8) Show SMILES CCOc1cc(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)c(Cl)cc1CN[C@@H]([C@@H](C)O)C(O)=O |r| Show InChI InChI=1S/C37H47ClN2O7/c1-4-45-34-21-35(31(38)20-25(34)22-39-36(24(3)41)37(43)44)47-33-13-12-29-28(9-5-10-30(29)33)27-8-6-11-32(23(27)2)46-19-7-16-40-17-14-26(42)15-18-40/h5-6,8-11,20-21,24,26,33,36,39,41-42H,4,7,12-19,22H2,1-3H3,(H,43,44)/t24-,33+,36+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021)
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