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SMILES: Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC(C)(C)O)cc1Cl

InChI Key: InChIKey=BBAKPQJZPNHFOA-KDXMTYKHSA-N

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482361   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482361
PNG
(US10919852, Compound TABLE 1.60)
Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC(C)(C)O)cc1Cl |r|
Show InChI InChI=1S/C42H49ClN4O5/c1-28-33(7-5-10-38(28)50-18-6-15-47-16-13-32(48)14-17-47)34-8-4-9-36-35(34)11-12-39(36)52-41-21-40(51-26-30-19-29(22-44)23-45-24-30)31(20-37(41)43)25-46-27-42(2,3)49/h4-5,7-10,19-21,23-24,32,39,46,48-49H,6,11-18,25-27H2,1-3H3/t39-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)

More data for this
Ligand-Target Pair