null

SMILES: Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC(C)(O)CC2)cc1Cl

InChI Key: InChIKey=MYOCPRVGDUQUFZ-RWYGWLOXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482370 (US10919852, Compound TABLE 1.69 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC(C)(O)CC2)cc1Cl |r| Show InChI InChI=1S/C44H51ClN4O5/c1-30-35(6-4-9-40(30)52-21-5-16-48-17-12-34(50)13-18-48)36-7-3-8-38-37(36)10-11-41(38)54-43-24-42(53-29-32-22-31(25-46)26-47-27-32)33(23-39(43)45)28-49-19-14-44(2,51)15-20-49/h3-4,6-9,22-24,26-27,34,41,50-51H,5,10-21,28-29H2,1-2H3/t41-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482370 (US10919852, Compound TABLE 1.69 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC(C)(O)CC2)cc1Cl |r| Show InChI InChI=1S/C44H51ClN4O5/c1-30-35(6-4-9-40(30)52-21-5-16-48-17-12-34(50)13-18-48)36-7-3-8-38-37(36)10-11-41(38)54-43-24-42(53-29-32-22-31(25-46)26-47-27-32)33(23-39(43)45)28-49-19-14-44(2,51)15-20-49/h3-4,6-9,22-24,26-27,34,41,50-51H,5,10-21,28-29H2,1-2H3/t41-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair