null

SMILES: C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2[C@@H](F)Cc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key: InChIKey=HDJBUMNEXYDRKU-NAUQLIQISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482382 (US10919852, Compound TABLE 1.81 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2[C@@H](F)Cc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H46ClFN4O7/c1-25-31(6-4-9-37(25)53-15-5-12-48-13-10-30(50)11-14-48)32-7-3-8-33-34(32)18-36(44)41(33)55-39-19-38(54-24-28-16-27(20-45)21-46-22-28)29(17-35(39)43)23-47-40(26(2)49)42(51)52/h3-4,6-9,16-17,19,21-22,26,30,36,40-41,47,49-50H,5,10-15,18,23-24H2,1-2H3,(H,51,52)/t26-,36+,40+,41-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482382 (US10919852, Compound TABLE 1.81 | US11708326, Comp...) Show SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(O[C@H]2[C@@H](F)Cc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2C)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C42H46ClFN4O7/c1-25-31(6-4-9-37(25)53-15-5-12-48-13-10-30(50)11-14-48)32-7-3-8-33-34(32)18-36(44)41(33)55-39-19-38(54-24-28-16-27(20-45)21-46-22-28)29(17-35(39)43)23-47-40(26(2)49)42(51)52/h3-4,6-9,16-17,19,21-22,26,30,36,40-41,47,49-50H,5,10-15,18,23-24H2,1-2H3,(H,51,52)/t26-,36+,40+,41-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair