null

SMILES: OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@@H](Oc4cc(OCc5cc(cc(c5)C#N)C#N)c(CNC[C@H]5CCC(=O)N5)cc4Cl)[C@@H](F)Cc23)C1

InChI Key: InChIKey=ZOLZKKOYNOAJMZ-UJSZENJDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482404 (US10919852, Compound TABLE 1.103 | US11708326, Com...) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@@H](Oc4cc(OCc5cc(cc(c5)C#N)C#N)c(CNC[C@H]5CCC(=O)N5)cc4Cl)[C@@H](F)Cc23)C1 |r| Show InChI InChI=1S/C42H40Cl2FN5O5/c43-35-15-28(20-48-21-29-8-9-40(52)49-29)38(54-24-27-13-25(18-46)12-26(14-27)19-47)17-39(35)55-42-33-6-1-4-31(34(33)16-36(42)45)32-5-2-7-37(41(32)44)53-11-3-10-50-22-30(51)23-50/h1-2,4-7,12-15,17,29-30,36,42,48,51H,3,8-11,16,20-24H2,(H,49,52)/t29-,36+,42-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482404 (US10919852, Compound TABLE 1.103 | US11708326, Com...) Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@@H](Oc4cc(OCc5cc(cc(c5)C#N)C#N)c(CNC[C@H]5CCC(=O)N5)cc4Cl)[C@@H](F)Cc23)C1 |r| Show InChI InChI=1S/C42H40Cl2FN5O5/c43-35-15-28(20-48-21-29-8-9-40(52)49-29)38(54-24-27-13-25(18-46)12-26(14-27)19-47)17-39(35)55-42-33-6-1-4-31(34(33)16-36(42)45)32-5-2-7-37(41(32)44)53-11-3-10-50-22-30(51)23-50/h1-2,4-7,12-15,17,29-30,36,42,48,51H,3,8-11,16,20-24H2,(H,49,52)/t29-,36+,42-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair