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SMILES: CC(CO)(NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCOCC3)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key: InChIKey=PNUZTIAFYKGGSG-ROLZWKQRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482432   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482432
PNG
(US10919852, Compound TABLE 1.131)
Show SMILES CC(CO)(NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCOCC3)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O |r|
Show InChI InChI=1S/C40H42Cl2N4O7/c1-40(25-47,39(48)49)45-23-28-18-33(41)37(19-36(28)52-24-27-17-26(20-43)21-44-22-27)53-34-10-9-30-29(5-2-6-31(30)34)32-7-3-8-35(38(32)42)51-14-4-11-46-12-15-50-16-13-46/h2-3,5-8,17-19,21-22,34,45,47H,4,9-16,23-25H2,1H3,(H,48,49)/t34-,40?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)

More data for this
Ligand-Target Pair